Advances in DNA Sequence-specific Agents: 4 by B. J. Chapman

By B. J. Chapman

This sequence encompasses layout, synthesis, software, and analytical tools (including medical and in vitro) for the research of those severe interactions. As our figuring out of the genome and proteome expands, normal advancements within the box of DNA series particular interplay tend to play an more and more very important function. therefore, manuscripts were solicited from specialists protecting a various variety of fields, reflecting the cross-disciplinary and dynamic nature of the series.

Volume four describes paintings at the amendment of DNA by means of AT particular anticancer medications, DNA alkylation occasions which contain metabolite new release, DNA series reputation by way of selective binders, bulged DNA microenvironments as molecular pursuits, DNA series particular binding via brief peptides and the research of DNA-protein interactions utilizing DNase I footprinting methodology.

Features comprise:
• specialist participants from the Biomedical world
• rising components of drug layout and healing applications
• Nucleic acid-protein interactions
• colour photos of molecular modeling analyses
• New and rising methodologies

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